The goal of this compendium on, “Sustainable Biological Systems for Agriculture: Emerging Issues in Nanotechnology, Biofertilizers, Wastewater, and Farm Machines” is to: guide the world engineering community on how to efficiently manage crop production; and introduce applications of nanotechnology. The reader must be aware that the dedication, commitment, honesty, and sincerity are most important factors in a dynamic manner for a complete success. It is not a one-time reading of this compendium. Read and follow every time, it is needed. To err is human. However, we must do our best. Always, there is a space for learning new experiences.